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Animal models for studying tumor microenvironment (TME) and resistance to lymphocytic infiltration
In cancer immunotherapy, cytotoxic T or NK cells need to engage cancer cells to initiate the killing. However, in clinical studies and in mouse models, some solid tumors are found with no lymphocytes. It is likely that these tumors will be resistant to all sorts of immunotherapies. Thus, restoring l...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154837/ https://www.ncbi.nlm.nih.gov/pubmed/29723108 http://dx.doi.org/10.1080/15384047.2018.1470722 |