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Novel insights into the epigenetics of diffuse glioma

Loss-of-function mutations of the chromatin regulator ATRX (α-thalassemia mental retardation X-linked) occur frequently in diffuse gliomas, but the molecular mechanisms by which ATRX inactivation promotes oncogenesis remain unclear. We recently reported that Atrx deficiency drives glioma-relevant ph...

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Detalles Bibliográficos
Autores principales: Danussi, Carla, Huse, Jason T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154842/
https://www.ncbi.nlm.nih.gov/pubmed/30263940
http://dx.doi.org/10.1080/23723556.2018.1472055