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CCPG1, an unconventional cargo receptor for ER-phagy, maintains pancreatic acinar cell health

ER stress-mediated induction of a new vertebrate-specific autophagy cargo receptor, CCPG1 (cell-cycle progression gene 1), drives degradation of endoplasmic reticulum. CCPG1 acts via ATG8-family interaction and, non-canonically, via discrete interactions with FIP200. CCPG1 ameliorates ER stress in t...

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Detalles Bibliográficos
Autores principales: Smith, Matthew D., Wilkinson, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154861/
https://www.ncbi.nlm.nih.gov/pubmed/30263939
http://dx.doi.org/10.1080/23723556.2018.1441631