A novel mechanism of SRRM4 in promoting neuroendocrine prostate cancer development via a pluripotency gene network

BACKGROUND: Prostate adenocarcinoma (AdPC) cells can undergo lineage switching to neuroendocrine cells and develop into therapy-resistant neuroendocrine prostate cancer (NEPC). While genomic/epigenetic alterations are shown to induce neuroendocrine differentiation via an intermediate stem-like state...

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Detalles Bibliográficos
Autores principales: Lee, Ahn R., Gan, Yu, Tang, Yuxin, Dong, Xuesen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154886/
https://www.ncbi.nlm.nih.gov/pubmed/30100395
http://dx.doi.org/10.1016/j.ebiom.2018.08.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154886/
https://www.ncbi.nlm.nih.gov/pubmed/30100395
http://dx.doi.org/10.1016/j.ebiom.2018.08.011

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