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A novel mechanism of SRRM4 in promoting neuroendocrine prostate cancer development via a pluripotency gene network

BACKGROUND: Prostate adenocarcinoma (AdPC) cells can undergo lineage switching to neuroendocrine cells and develop into therapy-resistant neuroendocrine prostate cancer (NEPC). While genomic/epigenetic alterations are shown to induce neuroendocrine differentiation via an intermediate stem-like state...

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Detalles Bibliográficos
Autores principales:	Lee, Ahn R., Gan, Yu, Tang, Yuxin, Dong, Xuesen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154886/ https://www.ncbi.nlm.nih.gov/pubmed/30100395 http://dx.doi.org/10.1016/j.ebiom.2018.08.011

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