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Fast design of arbitrary length loops in proteins using InteractiveRosetta
BACKGROUND: With increasing interest in ab initio protein design, there is a desire to be able to fully explore the design space of insertions and deletions. Nature inserts and deletes residues to optimize energy and function, but allowing variable length indels in the context of an interactive prot...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154894/ https://www.ncbi.nlm.nih.gov/pubmed/30249181 http://dx.doi.org/10.1186/s12859-018-2345-5 |