Associations among IGF-1, IGF2, IGF-1R, IGF-2R, IGFBP-3, insulin genetic polymorphisms and central precocious puberty in girls

BACKGROUND: Insulin and insulin-like growth factor (IGF)-1 coupled with growth hormone helps control timing of sexual maturation. Mutations and variants in multiple genes are associated with development or reduced risk of central precocious puberty (CPP). METHODS: We assessed single nucleotide polym...

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Detalles Bibliográficos
Autores principales: Chang, Hua-Pin, Yang, Shun-Fa, Wang, Shu-Li, Su, Pen-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154940/
https://www.ncbi.nlm.nih.gov/pubmed/30249230
http://dx.doi.org/10.1186/s12902-018-0271-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154940/
https://www.ncbi.nlm.nih.gov/pubmed/30249230
http://dx.doi.org/10.1186/s12902-018-0271-1

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