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Associations among IGF-1, IGF2, IGF-1R, IGF-2R, IGFBP-3, insulin genetic polymorphisms and central precocious puberty in girls

BACKGROUND: Insulin and insulin-like growth factor (IGF)-1 coupled with growth hormone helps control timing of sexual maturation. Mutations and variants in multiple genes are associated with development or reduced risk of central precocious puberty (CPP). METHODS: We assessed single nucleotide polym...

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Detalles Bibliográficos
Autores principales:	Chang, Hua-Pin, Yang, Shun-Fa, Wang, Shu-Li, Su, Pen-Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154940/ https://www.ncbi.nlm.nih.gov/pubmed/30249230 http://dx.doi.org/10.1186/s12902-018-0271-1

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