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The potential HLA Class I-restricted epitopes derived from LeIF and TSA of Leishmania donovani evoke anti-leishmania CD8+ T lymphocyte response

To explore new protective measure against visceral leishmaniasis, reverse vaccinology approach was employed to identify key immunogenic regions which can mediate long-term immunity. In-depth computational analysis revealed nine promiscuous epitopes which can possibly be presented by 46 human leukocy...

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Detalles Bibliográficos
Autores principales: Dikhit, Manas Ranjan, Das, Sushmita, Mahantesh, Vijaya, Kumar, Akhilesh, Singh, Ashish Kumar, Dehury, Budheswar, Rout, Ajaya Kumar, Ali, Vahab, Sahoo, Ganesh Chandra, Topno, Roshan Kamal, Pandey, Krishna, Das, V. N. R., Bimal, Sanjiva, Das, Pradeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154976/
https://www.ncbi.nlm.nih.gov/pubmed/30242172
http://dx.doi.org/10.1038/s41598-018-32040-x