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Comparison of interleukin-2-inducible kinase (ITK) inhibitors and potential for combination therapies for T-cell lymphoma

Patients with peripheral T-cell lymphomas generally have poor clinical outcomes with conventional chemotherapy. Recent advances have demonstrated that a large subgroup of PTCL are derived from follicular helper (Tfh) T-cells. These cases show a characteristic pattern of gene expression, which includ...

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Detalles Bibliográficos
Autores principales: Mamand, Sami, Allchin, Rebecca L., Ahearne, Matthew J., Wagner, Simon D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154993/
https://www.ncbi.nlm.nih.gov/pubmed/30242208
http://dx.doi.org/10.1038/s41598-018-32634-5