A Bioluminescent Cell Assay to Quantify Prion Protein Dimerization

The prion protein (PrP) is a cell surface protein that in disease misfolds and becomes infectious causing Creutzfeldt-Jakob disease in humans, scrapie in sheep, and chronic wasting disease in deer and elk. Little is known regarding the dimerization of PrP and its role in disease. We developed a biol...

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Detalles Bibliográficos
Autores principales: Wüsten, Katharina Annick, Reddy, Pasham Parameshwar, Smiyakin, Andrej, Bernis, Maria Eugenia, Tamgüney, Gültekin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155003/
https://www.ncbi.nlm.nih.gov/pubmed/30242186
http://dx.doi.org/10.1038/s41598-018-32581-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155003/
https://www.ncbi.nlm.nih.gov/pubmed/30242186
http://dx.doi.org/10.1038/s41598-018-32581-1

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