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Misoprostol regulates Bnip3 repression and alternative splicing to control cellular calcium homeostasis during hypoxic stress

The cellular response to hypoxia involves the activation of a conserved pathway for gene expression regulated by the transcription factor complex called hypoxia-inducible factor (HIF). This pathway has been implicated in both the adaptive response to hypoxia and in several hypoxic-ischemic-related p...

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Detalles Bibliográficos
Autores principales: Field, Jared T., Martens, Matthew D., Mughal, Wajihah, Hai, Yan, Chapman, Donald, Hatch, Grant M., Ivanco, Tammy L., Diehl-Jones, William, Gordon, Joseph W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155004/
https://www.ncbi.nlm.nih.gov/pubmed/30275982
http://dx.doi.org/10.1038/s41420-018-0104-z