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Impaired wound healing in type 1 diabetes is dependent on 5-lipoxygenase products

Type 1 diabetes is associated with systemic low grade inflammation (LGI). We have previously shown that LGI in diabetic mice depends on systemic circulation of leukotriene (LTB(4)) which potentiates the toll-like/IL1β receptors response in macrophages. Impaired wound healing is an important co-morbi...

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Detalles Bibliográficos
Autores principales: Ramalho, Theresa, Filgueiras, Luciano, Silva-Jr, Ildefonso Alves, Pessoa, Ana Flavia Marçal, Jancar, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155046/
https://www.ncbi.nlm.nih.gov/pubmed/30242286
http://dx.doi.org/10.1038/s41598-018-32589-7