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Back-translating behavioral intervention for autism spectrum disorders to mice with blunted reward restores social abilities

The mu opioid receptor (MOR) plays a critical role in modulating social behavior in humans and animals. Accordingly, MOR null mice display severe alterations in their social repertoire as well as multiple other behavioral deficits, recapitulating core and secondary symptoms of autism spectrum disord...

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Detalles Bibliográficos
Autores principales: Pujol, Camille N., Pellissier, Lucie P., Clément, Céline, Becker, Jérôme A. J., Le Merrer, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155047/
https://www.ncbi.nlm.nih.gov/pubmed/30242222
http://dx.doi.org/10.1038/s41398-018-0247-y