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Evolutionarily-conserved MZIP2 is essential for crossover formation in mammalian meiosis

During meiosis, formation of crossovers—the physical links that ensure the segregation of homologous chromosomes—requires a group of evolutionarily conserved ZMM proteins. In budding yeast, three ZMM proteins, Zip2, Spo16, and Zip4, form a trimeric complex to bind recombination intermediates and pro...

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Detalles Bibliográficos
Autores principales: Zhang, Qianting, Shao, Jingchen, Fan, Heng-Yu, Yu, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155065/
https://www.ncbi.nlm.nih.gov/pubmed/30272023
http://dx.doi.org/10.1038/s42003-018-0154-z