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A tissue-specific self-interacting chromatin domain forms independently of enhancer-promoter interactions

Self-interacting chromatin domains encompass genes and their cis-regulatory elements; however, the three-dimensional form a domain takes, whether this relies on enhancer–promoter interactions, and the processes necessary to mediate the formation and maintenance of such domains, remain unclear. To ex...

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Detalles Bibliográficos
Autores principales: Brown, Jill M., Roberts, Nigel A., Graham, Bryony, Waithe, Dominic, Lagerholm, Christoffer, Telenius, Jelena M., De Ornellas, Sara, Oudelaar, A. Marieke, Scott, Caroline, Szczerbal, Izabela, Babbs, Christian, Kassouf, Mira T., Hughes, Jim R., Higgs, Douglas R., Buckle, Veronica J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155075/
https://www.ncbi.nlm.nih.gov/pubmed/30242161
http://dx.doi.org/10.1038/s41467-018-06248-4