Biomechanical interplay between anisotropic re-organization of cells and the surrounding matrix underlies transition to invasive cancer spread

The root cause of cancer mortality and morbidity is the metastatic spread of the primary tumor, but underlying mechanisms remain elusive. Here we investigate biomechanical interactions that may accompany invasive spread of melanoma cells. We find that metastatic cells can exert considerable traction...

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Detalles Bibliográficos
Autores principales: Kim, Deok-Ho, Ewald, Andrew J., Park, JinSeok, Kshitiz, Kwak, Moonkyu, Gray, Ryan S., Su, Chia-Yi, Seo, Jayhyun, An, Steven S., Levchenko, Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155084/
https://www.ncbi.nlm.nih.gov/pubmed/30242256
http://dx.doi.org/10.1038/s41598-018-32010-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155084/
https://www.ncbi.nlm.nih.gov/pubmed/30242256
http://dx.doi.org/10.1038/s41598-018-32010-3

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