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A naturally protective epitope of limited variability as an influenza vaccine target

Current antigenic targets for influenza vaccine development are either highly immunogenic epitopes of high variability or conserved epitopes of low immunogenicity. This requires continuous update of the variable epitopes in the vaccine formulation or boosting of immunity to invariant epitopes of low...

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Detalles Bibliográficos
Autores principales: Thompson, Craig P., Lourenço, José, Walters, Adam A., Obolski, Uri, Edmans, Matthew, Palmer, Duncan S., Kooblall, Kreepa, Carnell, George W., O’Connor, Daniel, Bowden, Thomas A., Pybus, Oliver G., Pollard, Andrew J., Temperton, Nigel J., Lambe, Teresa, Gilbert, Sarah C., Gupta, Sunetra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155085/
https://www.ncbi.nlm.nih.gov/pubmed/30242149
http://dx.doi.org/10.1038/s41467-018-06228-8