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Parkin-dependent regulation of the MCU complex component MICU1

The mitochondrial Ca(2+) uniporter machinery is a multiprotein complex composed by the Ca(2+) selective pore-forming subunit, the mitochondrial uniporter (MCU), and accessory proteins, including MICU1, MICU2 and EMRE. Their concerted action is required to fine-tune the uptake of Ca(2+) into the mito...

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Detalles Bibliográficos
Autores principales: Matteucci, Alessandra, Patron, Maria, Vecellio Reane, Denis, Gastaldello, Stefano, Amoroso, Salvatore, Rizzuto, Rosario, Brini, Marisa, Raffaello, Anna, Calì, Tito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155109/
https://www.ncbi.nlm.nih.gov/pubmed/30242232
http://dx.doi.org/10.1038/s41598-018-32551-7