The Fab fragment of anti-IgE Cε2 domain prevents allergic reactions through interacting with IgE-FcεRIα complex on rat mast cells

Immunoglobulin E (IgE) plays a central role in the pathogenesis of Type I hypersensitivity through interaction with a high-affinity receptor (FcεRIα). For therapeutic applications, substantial attention has been focused recently on the blockade of the IgE interaction with FcεRIα. While exploring bet...

Descripción completa

Detalles Bibliográficos
Autores principales: Hirano, Takao, Koyanagi, Akemi, Kotoshiba, Kaoru, Shinkai, Yoichi, Kasai, Masataka, Ando, Tomoaki, Kaitani, Ayako, Okumura, Ko, Kitaura, Jiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155129/
https://www.ncbi.nlm.nih.gov/pubmed/30250145
http://dx.doi.org/10.1038/s41598-018-32200-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155129/
https://www.ncbi.nlm.nih.gov/pubmed/30250145
http://dx.doi.org/10.1038/s41598-018-32200-z

Ejemplares similares