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The Fab fragment of anti-IgE Cε2 domain prevents allergic reactions through interacting with IgE-FcεRIα complex on rat mast cells

Immunoglobulin E (IgE) plays a central role in the pathogenesis of Type I hypersensitivity through interaction with a high-affinity receptor (FcεRIα). For therapeutic applications, substantial attention has been focused recently on the blockade of the IgE interaction with FcεRIα. While exploring bet...

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Detalles Bibliográficos
Autores principales:	Hirano, Takao, Koyanagi, Akemi, Kotoshiba, Kaoru, Shinkai, Yoichi, Kasai, Masataka, Ando, Tomoaki, Kaitani, Ayako, Okumura, Ko, Kitaura, Jiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155129/ https://www.ncbi.nlm.nih.gov/pubmed/30250145 http://dx.doi.org/10.1038/s41598-018-32200-z

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