Restoration of GLP-1 secretion by Berberine is associated with protection of colon enterocytes from mitochondrial overheating in diet-induced obese mice

OBJECTIVE: L-cell dysfunction is reported for GLP-1 reduction in type 2 diabetes. However, the mechanism of dysfunction remains unknown. In this study, we examined mitochondrial function in the mechanistic study in diet-induced obese (DIO) mice. SUBJECTS: C57BL/6 mice were fed a high-fat diet (HFD)...

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Detalles Bibliográficos
Autores principales: Sun, Yongning, Jin, Chenxi, Zhang, Xiaoying, Jia, Weiping, Le, Jiamei, Ye, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155143/
https://www.ncbi.nlm.nih.gov/pubmed/30250193
http://dx.doi.org/10.1038/s41387-018-0061-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155143/
https://www.ncbi.nlm.nih.gov/pubmed/30250193
http://dx.doi.org/10.1038/s41387-018-0061-x

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