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SIRT1 suppresses the migration and invasion of gastric cancer by regulating ARHGAP5 expression

Gastric cancer (GC) ranks among the top five malignant tumors worldwide by the incidence and mortality rate. However, the mechanisms underlying its progression are poorly understood. In this study, we investigated the role of SIRT1, a class III deacetylase, in the invasion and metastasis of GC. Here...

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Detalles Bibliográficos
Autores principales: Dong, Guoying, Wang, Bo, An, Yifei, Li, Juan, Wang, Xin, Jia, Jihui, Yang, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155157/
https://www.ncbi.nlm.nih.gov/pubmed/30250020
http://dx.doi.org/10.1038/s41419-018-1033-8