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Parkin-mediated mitophagy as a potential therapeutic target for intervertebral disc degeneration

Intervertebral disc degeneration (IDD) is a complicated pathological condition blamed for low back pain. Mitochondrion is of vital importance for cellular homeostasis, and mitochondrial dysfunction is considered to be one of the major causes of cellular damage. Mitophagy is a cellular process to eli...

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Detalles Bibliográficos
Autores principales: Zhang, Zengjie, Xu, Tianzhen, Chen, Jiaoxiang, Shao, Zhenxuan, Wang, Ke, Yan, Yingchao, Wu, Congcong, Lin, Jialiang, Wang, Haoli, Gao, Weiyang, Zhang, Xiaolei, Wang, Xiangyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155159/
https://www.ncbi.nlm.nih.gov/pubmed/30250268
http://dx.doi.org/10.1038/s41419-018-1024-9