Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks

Homologous recombination (HR) is a crucial pathway for the repair of DNA double-strand breaks. BRCA1/2 breast cancer proteins are key players in HR via their mediation of RAD51 nucleofilament formation and function; however, their individual roles and crosstalk in vivo are unknown. Here we use super...

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Detalles Bibliográficos
Autores principales: Whelan, Donna R., Lee, Wei Ting C., Yin, Yandong, Ofri, Dylan M., Bermudez-Hernandez, Keria, Keegan, Sarah, Fenyo, David, Rothenberg, Eli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155164/
https://www.ncbi.nlm.nih.gov/pubmed/30250272
http://dx.doi.org/10.1038/s41467-018-06435-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155164/
https://www.ncbi.nlm.nih.gov/pubmed/30250272
http://dx.doi.org/10.1038/s41467-018-06435-3

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