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New Chiral Ebselen Analogues with Antioxidant and Cytotoxic Potential

New chiral camphane-derived benzisoselenazol-3(2H)-ones and corresponding diselenides have been synthetized using a convenient one-pot procedure. Se-N bond was efficiently converted to an Se-Se bond, which could also be easily re-oxidized to the initial benzisoselenazolone moiety. The antioxidant ac...

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Detalles Bibliográficos
Autores principales: Pacuła, Agata J., Kaczor, Katarzyna B., Antosiewicz, Jędrzej, Janecka, Anna, Długosz, Angelika, Janecki, Tomasz, Wojtczak, Andrzej, Ścianowski, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155185/
https://www.ncbi.nlm.nih.gov/pubmed/28335518
http://dx.doi.org/10.3390/molecules22030492