Morphological Evaluation of Meta-stable Oligomers of α-Synuclein with Small-Angle Neutron Scattering

Amyloidogenesis of α-synuclein (αS) is considered to be a pathological phenomenon related to Parkinson’s disease (PD). As a key component to reveal the fibrillation mechanism and toxicity, we have investigated an oligomeric species of αS capable of exhibiting the unit-assembly process leading to acc...

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Detalles Bibliográficos
Autores principales: Bhak, Ghibom, Lee, Soonkoo, Kim, Tae-Hwan, Lee, Ji-Hye, Yang, Jee Eun, Joo, Keehyoung, Lee, Jooyoung, Char, Kookheon, Paik, Seung R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155208/
https://www.ncbi.nlm.nih.gov/pubmed/30250173
http://dx.doi.org/10.1038/s41598-018-32655-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155208/
https://www.ncbi.nlm.nih.gov/pubmed/30250173
http://dx.doi.org/10.1038/s41598-018-32655-0

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