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Morphological Evaluation of Meta-stable Oligomers of α-Synuclein with Small-Angle Neutron Scattering
Amyloidogenesis of α-synuclein (αS) is considered to be a pathological phenomenon related to Parkinson’s disease (PD). As a key component to reveal the fibrillation mechanism and toxicity, we have investigated an oligomeric species of αS capable of exhibiting the unit-assembly process leading to acc...
Autores principales: | Bhak, Ghibom, Lee, Soonkoo, Kim, Tae-Hwan, Lee, Ji-Hye, Yang, Jee Eun, Joo, Keehyoung, Lee, Jooyoung, Char, Kookheon, Paik, Seung R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155208/ https://www.ncbi.nlm.nih.gov/pubmed/30250173 http://dx.doi.org/10.1038/s41598-018-32655-0 |
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