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Loperamide, pimozide, and STF-62247 trigger autophagy-dependent cell death in glioblastoma cells

Autophagy is a well-described degradation mechanism that promotes cell survival upon nutrient starvation and other forms of cellular stresses. In addition, there is growing evidence showing that autophagy can exert a lethal function via autophagic cell death (ACD). As ACD has been implicated in apop...

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Detalles Bibliográficos
Autores principales: Zielke, Svenja, Meyer, Nina, Mari, Muriel, Abou-El-Ardat, Khalil, Reggiori, Fulvio, van Wijk, Sjoerd J. L., Kögel, Donat, Fulda, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155211/
https://www.ncbi.nlm.nih.gov/pubmed/30250198
http://dx.doi.org/10.1038/s41419-018-1003-1