3-Substituted N-Benzylpyrazine-2-carboxamide Derivatives: Synthesis, Antimycobacterial and Antibacterial Evaluation

A series of substituted N-benzyl-3-chloropyrazine-2-carboxamides were prepared as positional isomers of 5-chloro and 6-chloro derivatives, prepared previously. During the aminolysis of the acyl chloride, the simultaneous substitution of chlorine with benzylamino moiety gave rise to N-benzyl-3-(benzy...

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Detalles Bibliográficos
Autores principales: Semelková, Lucia, Janďourek, Ondřej, Konečná, Klára, Paterová, Pavla, Navrátilová, Lucie, Trejtnar, František, Kubíček, Vladimír, Kuneš, Jiří, Doležal, Martin, Zitko, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155222/
https://www.ncbi.nlm.nih.gov/pubmed/28335571
http://dx.doi.org/10.3390/molecules22030495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155222/
https://www.ncbi.nlm.nih.gov/pubmed/28335571
http://dx.doi.org/10.3390/molecules22030495

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