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CcpA Coordinates Growth/Damage Balance for Streptococcus pyogenes Pathogenesis

To achieve maximum fitness, pathogens must balance growth with tissue damage, coordinating metabolism and virulence factor expression. In the gram-positive bacterium Streptococcus pyogenes, the DNA-binding transcriptional regulator Carbon Catabolite Protein A (CcpA) is a master regulator of both car...

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Detalles Bibliográficos
Autores principales: Paluscio, Elyse, Watson, Michael E., Caparon, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155242/
https://www.ncbi.nlm.nih.gov/pubmed/30250043
http://dx.doi.org/10.1038/s41598-018-32558-0