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CcpA Coordinates Growth/Damage Balance for Streptococcus pyogenes Pathogenesis
To achieve maximum fitness, pathogens must balance growth with tissue damage, coordinating metabolism and virulence factor expression. In the gram-positive bacterium Streptococcus pyogenes, the DNA-binding transcriptional regulator Carbon Catabolite Protein A (CcpA) is a master regulator of both car...
Autores principales: | Paluscio, Elyse, Watson, Michael E., Caparon, Michael G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155242/ https://www.ncbi.nlm.nih.gov/pubmed/30250043 http://dx.doi.org/10.1038/s41598-018-32558-0 |
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