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Synthesis of Substituted α-Trifluoromethyl Piperidinic Derivatives

A comprehensive survey of pathways leading to the generation of α-trifluoromethyl monocyclic piperidinic derivatives is provided (65 references). These compounds have been synthesized either from 6-membered rings e.g., pipecolic acid or lactam derivatives by introduction a trifluoromethyl group, fro...

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Detalles Bibliográficos
Autores principales: Rioton, Sarah, Pardo, Domingo Gomez, Cossy, Janine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155269/
https://www.ncbi.nlm.nih.gov/pubmed/28335499
http://dx.doi.org/10.3390/molecules22030483