Chroman-4-One Derivatives Targeting Pteridine Reductase 1 and Showing Anti-Parasitic Activity

Flavonoids have previously been identified as antiparasitic agents and pteridine reductase 1 (PTR1) inhibitors. Herein, we focus our attention on the chroman-4-one scaffold. Three chroman-4-one analogues (1–3) of previously published chromen-4-one derivatives were synthesized and biologically evalua...

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Detalles Bibliográficos
Autores principales: Di Pisa, Flavio, Landi, Giacomo, Dello Iacono, Lucia, Pozzi, Cecilia, Borsari, Chiara, Ferrari, Stefania, Santucci, Matteo, Santarem, Nuno, Cordeiro-da-Silva, Anabela, Moraes, Carolina B., Alcantara, Laura M., Fontana, Vanessa, Freitas-Junior, Lucio H., Gul, Sheraz, Kuzikov, Maria, Behrens, Birte, Pöhner, Ina, Wade, Rebecca C., Costi, Maria Paola, Mangani, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155272/
https://www.ncbi.nlm.nih.gov/pubmed/28282886
http://dx.doi.org/10.3390/molecules22030426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155272/
https://www.ncbi.nlm.nih.gov/pubmed/28282886
http://dx.doi.org/10.3390/molecules22030426

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