Luteolin Inhibits Fibrillary β-Amyloid(1–40)-Induced Inflammation in a Human Blood-Brain Barrier Model by Suppressing the p38 MAPK-Mediated NF-κB Signaling Pathways

Amyloid-β peptides (Aβ) exist in several forms and are known as key modulators of Alzheimer’s disease (AD). Fibrillary Aβ (fAβ) has been found to disrupt the blood-brain barrier (BBB) by triggering and promoting inflammation. In this study, luteolin, a naturally occurring flavonoid that has shown be...

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Detalles Bibliográficos
Autores principales: Zhang, Jun-Xia, Xing, Jian-Guo, Wang, Lin-Lin, Jiang, Hai-Lun, Guo, Shui-Long, Liu, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155314/
https://www.ncbi.nlm.nih.gov/pubmed/28245546
http://dx.doi.org/10.3390/molecules22030334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155314/
https://www.ncbi.nlm.nih.gov/pubmed/28245546
http://dx.doi.org/10.3390/molecules22030334

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