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SIRT3 deficiency leads to induction of abnormal glycolysis in diabetic kidney with fibrosis

The regulation of aberrant glucose metabolism in diabetes associated-kidney fibrosis is not well known. In this study we found the suppression of SIRT3 protein level in diabetic kidney, displays responsibility in fibrogenic programming associated with aberrant glycolysis and such abnormal glycolysis...

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Detalles Bibliográficos
Autores principales: Srivastava, Swayam Prakash, Li, Jinpeng, Kitada, Munehiro, Fujita, Hiroki, Yamada, Yuichiro, Goodwin, Julie E., Kanasaki, Keizo, Koya, Daisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155322/
https://www.ncbi.nlm.nih.gov/pubmed/30250024
http://dx.doi.org/10.1038/s41419-018-1057-0