Enhanced Prediction of Hot Spots at Protein-Protein Interfaces Using Extreme Gradient Boosting

Identification of hot spots, a small portion of protein-protein interface residues that contribute the majority of the binding free energy, can provide crucial information for understanding the function of proteins and studying their interactions. Based on our previous method (PredHS), we propose a...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Hao, Liu, Chuyao, Deng, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155324/
https://www.ncbi.nlm.nih.gov/pubmed/30250210
http://dx.doi.org/10.1038/s41598-018-32511-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155324/
https://www.ncbi.nlm.nih.gov/pubmed/30250210
http://dx.doi.org/10.1038/s41598-018-32511-1

Ejemplares similares