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Enhanced Prediction of Hot Spots at Protein-Protein Interfaces Using Extreme Gradient Boosting
Identification of hot spots, a small portion of protein-protein interface residues that contribute the majority of the binding free energy, can provide crucial information for understanding the function of proteins and studying their interactions. Based on our previous method (PredHS), we propose a...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155324/ https://www.ncbi.nlm.nih.gov/pubmed/30250210 http://dx.doi.org/10.1038/s41598-018-32511-1 |