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Microfluidic deposition for resolving single-molecule protein architecture and heterogeneity
Scanning probe microscopy provides a unique window into the morphology, mechanics, and structure of proteins and their complexes on the nanoscale. Such measurements require, however, deposition of samples onto substrates. This process can affect conformations and assembly states of the molecular spe...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155325/ https://www.ncbi.nlm.nih.gov/pubmed/30250131 http://dx.doi.org/10.1038/s41467-018-06345-4 |