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Microfluidic deposition for resolving single-molecule protein architecture and heterogeneity

Scanning probe microscopy provides a unique window into the morphology, mechanics, and structure of proteins and their complexes on the nanoscale. Such measurements require, however, deposition of samples onto substrates. This process can affect conformations and assembly states of the molecular spe...

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Detalles Bibliográficos
Autores principales: Ruggeri, Francesco Simone, Charmet, Jerome, Kartanas, Tadas, Peter, Quentin, Chia, Sean, Habchi, Johnny, Dobson, Christopher M., Vendruscolo, Michele, Knowles, Tuomas P. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155325/
https://www.ncbi.nlm.nih.gov/pubmed/30250131
http://dx.doi.org/10.1038/s41467-018-06345-4