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E4BP4 promotes thyroid cancer proliferation by modulating iron homeostasis through repression of hepcidin

Iron homeostasis is critical to mammals, and dysregulation in iron homeostasis usually leads to severe disorders including various cancers. Massive hepcidin secretion is an indicator of thyroid cancer, but the molecular mechanisms responsible for this dysregulation are unknown. Hepcidin secretion fr...

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Detalles Bibliográficos
Autores principales: Zhou, Qinyi, Chen, Jun, Feng, Jialin, Wang, Jiadong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155336/
https://www.ncbi.nlm.nih.gov/pubmed/30250199
http://dx.doi.org/10.1038/s41419-018-1001-3