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E4BP4 promotes thyroid cancer proliferation by modulating iron homeostasis through repression of hepcidin
Iron homeostasis is critical to mammals, and dysregulation in iron homeostasis usually leads to severe disorders including various cancers. Massive hepcidin secretion is an indicator of thyroid cancer, but the molecular mechanisms responsible for this dysregulation are unknown. Hepcidin secretion fr...
Autores principales: | Zhou, Qinyi, Chen, Jun, Feng, Jialin, Wang, Jiadong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155336/ https://www.ncbi.nlm.nih.gov/pubmed/30250199 http://dx.doi.org/10.1038/s41419-018-1001-3 |
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