Facial Regioselective Synthesis of Novel Bioactive Spiropyrrolidine/Pyrrolizine-Oxindole Derivatives via a Three Components Reaction as Potential Antimicrobial Agents

This article presents the synthesis of new derivatives of spirooxindole-spiropiperidinone- pyrrolidines 6a–j and spirooxindole-spiropiperidinone-pyrrolizines 8a–j, through a 1,3-dipolar cycloaddition reaction of azomethineylides generated from isatin, sarcosine, and l-proline, through a decarboxylat...

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Detalles Bibliográficos
Autores principales: Hassaneen, Huwaida M. E., Eid, Elshimaa M., Eid, Hamid A., Farghaly, Thoraya A., Mabkhot, Yahia Nasser
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155345/
https://www.ncbi.nlm.nih.gov/pubmed/28245641
http://dx.doi.org/10.3390/molecules22030357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155345/
https://www.ncbi.nlm.nih.gov/pubmed/28245641
http://dx.doi.org/10.3390/molecules22030357

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