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Facial Regioselective Synthesis of Novel Bioactive Spiropyrrolidine/Pyrrolizine-Oxindole Derivatives via a Three Components Reaction as Potential Antimicrobial Agents

This article presents the synthesis of new derivatives of spirooxindole-spiropiperidinone- pyrrolidines 6a–j and spirooxindole-spiropiperidinone-pyrrolizines 8a–j, through a 1,3-dipolar cycloaddition reaction of azomethineylides generated from isatin, sarcosine, and l-proline, through a decarboxylat...

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Detalles Bibliográficos
Autores principales:	Hassaneen, Huwaida M. E., Eid, Elshimaa M., Eid, Hamid A., Farghaly, Thoraya A., Mabkhot, Yahia Nasser
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155345/ https://www.ncbi.nlm.nih.gov/pubmed/28245641 http://dx.doi.org/10.3390/molecules22030357

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