Rapamycin and fasting sustain autophagy response activated by ischemia/reperfusion injury and promote retinal ganglion cell survival

Autophagy, the cellular process responsible for degradation and recycling of cytoplasmic components through the autophagosomal–lysosomal pathway, is fundamental for neuronal homeostasis and its deregulation has been identified as a hallmark of neurodegeneration. Retinal hypoxic–ischemic events occur...

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Detalles Bibliográficos
Autores principales: Russo, Rossella, Varano, Giuseppe Pasquale, Adornetto, Annagrazia, Nazio, Francesca, Tettamanti, Gianluca, Girardello, Rossana, Cianfanelli, Valentina, Cavaliere, Federica, Morrone, Luigi Antonio, Corasaniti, Maria Tiziana, Cecconi, Francesco, Bagetta, Giacinto, Nucci, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155349/
https://www.ncbi.nlm.nih.gov/pubmed/30250019
http://dx.doi.org/10.1038/s41419-018-1044-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155349/
https://www.ncbi.nlm.nih.gov/pubmed/30250019
http://dx.doi.org/10.1038/s41419-018-1044-5

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