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Rapamycin and fasting sustain autophagy response activated by ischemia/reperfusion injury and promote retinal ganglion cell survival
Autophagy, the cellular process responsible for degradation and recycling of cytoplasmic components through the autophagosomal–lysosomal pathway, is fundamental for neuronal homeostasis and its deregulation has been identified as a hallmark of neurodegeneration. Retinal hypoxic–ischemic events occur...
Autores principales: | Russo, Rossella, Varano, Giuseppe Pasquale, Adornetto, Annagrazia, Nazio, Francesca, Tettamanti, Gianluca, Girardello, Rossana, Cianfanelli, Valentina, Cavaliere, Federica, Morrone, Luigi Antonio, Corasaniti, Maria Tiziana, Cecconi, Francesco, Bagetta, Giacinto, Nucci, Carlo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155349/ https://www.ncbi.nlm.nih.gov/pubmed/30250019 http://dx.doi.org/10.1038/s41419-018-1044-5 |
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