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A General Asymmetric Synthesis of (R)-Matsutakeol and Flavored Analogs

An efficient and practical synthetic route toward chiral matsutakeol and analogs was developed by asymmetric addition of terminal alkyne to aldehydes. (R)-matsutakeol and other flavored substances were feasibly synthesized from various alkylaldehydes in high yield (up to 49.5%, in three steps) and e...

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Detalles Bibliográficos
Autores principales: Liu, Jia, Li, Honglian, Zheng, Chao, Lu, Shichao, Guo, Xianru, Yin, Xinming, Na, Risong, Yu, Bin, Wang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155351/
https://www.ncbi.nlm.nih.gov/pubmed/28264452
http://dx.doi.org/10.3390/molecules22030364