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Positive selection in coding regions and motif duplication in regulatory regions of bottlenose dolphin MHC class II genes
The vertebrate immune response is mediated through highly adaptive, quickly evolving cell surface receptors, the major histocompatibility complex (MHC). MHC molecules bind and present a diverse array of pathogenic molecules and trigger a cascade of defenses. Use of MHC variation as a marker for popu...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155461/ https://www.ncbi.nlm.nih.gov/pubmed/30252841 http://dx.doi.org/10.1371/journal.pone.0203450 |