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Positive selection in coding regions and motif duplication in regulatory regions of bottlenose dolphin MHC class II genes

The vertebrate immune response is mediated through highly adaptive, quickly evolving cell surface receptors, the major histocompatibility complex (MHC). MHC molecules bind and present a diverse array of pathogenic molecules and trigger a cascade of defenses. Use of MHC variation as a marker for popu...

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Detalles Bibliográficos
Autores principales: Pagán, Heidi J. T., Ferrer, Tatiana, O’Corry-Crowe, Greg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155461/
https://www.ncbi.nlm.nih.gov/pubmed/30252841
http://dx.doi.org/10.1371/journal.pone.0203450