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An Engineered Human Fibroblast Growth Factor-1 Derivative, TTHX1114, Ameliorates Short-term Corneal Nitrogen Mustard Injury in Rabbit Organ Cultures

PURPOSE: Organ cultures of rabbit corneas have been used to ascertain the effectiveness of a human fibroblast growth factor (FGF)-1 derivative (TTHX1114), lacking cysteine residues, to protect against and/or repair epithelial lesions following exposure to nitrogen mustard (NM). METHODS: Rabbit corne...

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Detalles Bibliográficos
Autores principales: Eveleth, David D., Eveleth, Jennifer J., Subramaniam, Amuthakannan, Hahn, Rita, Zhou, Peihong, Gordon, Marion K., Bradshaw, Ralph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155473/
https://www.ncbi.nlm.nih.gov/pubmed/30267094
http://dx.doi.org/10.1167/iovs.18-24568