Pharmacologic control of oxidative stress and inflammation determines whether diabetic glomerulosclerosis progresses or decreases: A pilot study in sclerosis-prone mice

Diabetic kidney disease (DKD) is characterized by progressive glomerulosclerosis (GS). ROP mice have a sclerosis-prone phenotype. However, they develop severe, rapidly progressive GS when rendered diabetic. Since GS also develops in aged C57Bl6 mice, and can be reversed using bone marrow from young...

Descripción completa

Detalles Bibliográficos
Autores principales: Grosjean, Fabrizio, Yubero-Serrano, Elena M., Zheng, Feng, Esposito, Vittoria, Swamy, Shobha, Elliot, Sharon J., Cai, Weijing, Vlassara, Helen, Salem, Fadi, Striker, Gary E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155507/
https://www.ncbi.nlm.nih.gov/pubmed/30252878
http://dx.doi.org/10.1371/journal.pone.0204366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155507/
https://www.ncbi.nlm.nih.gov/pubmed/30252878
http://dx.doi.org/10.1371/journal.pone.0204366

Ejemplares similares