Pharmacologic control of oxidative stress and inflammation determines whether diabetic glomerulosclerosis progresses or decreases: A pilot study in sclerosis-prone mice

Diabetic kidney disease (DKD) is characterized by progressive glomerulosclerosis (GS). ROP mice have a sclerosis-prone phenotype. However, they develop severe, rapidly progressive GS when rendered diabetic. Since GS also develops in aged C57Bl6 mice, and can be reversed using bone marrow from young...

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Detalles Bibliográficos
Autores principales: Grosjean, Fabrizio, Yubero-Serrano, Elena M., Zheng, Feng, Esposito, Vittoria, Swamy, Shobha, Elliot, Sharon J., Cai, Weijing, Vlassara, Helen, Salem, Fadi, Striker, Gary E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155507/
https://www.ncbi.nlm.nih.gov/pubmed/30252878
http://dx.doi.org/10.1371/journal.pone.0204366

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