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Pharmacologic control of oxidative stress and inflammation determines whether diabetic glomerulosclerosis progresses or decreases: A pilot study in sclerosis-prone mice
Diabetic kidney disease (DKD) is characterized by progressive glomerulosclerosis (GS). ROP mice have a sclerosis-prone phenotype. However, they develop severe, rapidly progressive GS when rendered diabetic. Since GS also develops in aged C57Bl6 mice, and can be reversed using bone marrow from young...
Autores principales: | Grosjean, Fabrizio, Yubero-Serrano, Elena M., Zheng, Feng, Esposito, Vittoria, Swamy, Shobha, Elliot, Sharon J., Cai, Weijing, Vlassara, Helen, Salem, Fadi, Striker, Gary E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155507/ https://www.ncbi.nlm.nih.gov/pubmed/30252878 http://dx.doi.org/10.1371/journal.pone.0204366 |
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